Product Detail
Product NameNDRG1 Rabbit mAb
Clone No.JM32-02
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IHC, IP
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names42 kDa antibody
Anti GC4 antibody
cap43 antibody
cmt4d antibody
Differentiation related gene1 protein antibody
Differentiation-related gene 1 protein antibody
Drg 1 antibody
DRG-1 antibody
drg1 antibody
gc4 antibody
GC4 antibody
antibody
hmsnl antibody
Human mRNA for RTP complete cds antibody
N myc downstream regulated gene 1 antibody
N myc downstream regulated gene 1 protein antibody
N-myc downstream-regulated gene 1 protein antibody
Ndr 1 antibody
ndr1 antibody
NDRG 1 antibody
Ndrg1 antibody
NDRG1 protein antibody
NDRG1_HUMAN antibody
Nickel specific induction protein antibody
Nickel specific induction protein Cap43 antibody
Nickel-specific induction protein Cap43 antibody
nmsl antibody
Nmyc downstream regulated antibody
Nmyc downstream regulated gene1 antibody
Nmyc downstream regulated gene1 protein antibody
Protein NDRG1 antibody
Protein regulated by oxygen 1 antibody
Protein regulated by oxygen1 antibody
Proxy1 antibody
Reduced in tumor antibody
Reducin antibody
Reducing agents and tunicamycin responsive protein antibody
Reducing agents and tunicamycin-responsive protein antibody
Rit42 antibody
RTP antibody
targ1 antibody
TDD5 antibody
tdds antibody
Tunicamycin responsive protein antibody
Accession NoSwiss-Prot#:Q92597
Uniprot
Q92597
Gene ID
10397;
Calculated MW43 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
IP: 1:50
Western blot analysis of NDRG1 on SW480 cell (1) and mouse eye tissue (2) lysate using anti-NDRG1 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-NDRG1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-NDRG1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-NDRG1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NDRG1 antibody. Counter stained with hematoxylin.
ICC staining NDRG1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining NDRG1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
The N-myc downstream regulated gene (NDRG) family is comprised of four members, NDRG1 (also designated Drg1, RTP, rit42, Cap43 and Ndr1), NDRG2, NDRG3 and NDRG4, which share 57-65% homology. The NDRG1 gene, which maps to human chromosome 8q24.22, is evolutionarily conserved and is similarly regulated in humans, mice and rats . Like NDRG2 and NDRG3, NDRG1 is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation. The gene encoding NDRG3 maps to human chromosome 20q11.23 and is predominantly expressed in testis, prostate and ovary, which suggests it may play a role in spermatogenesis.
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