Product Detail
Product NamePKC mu Rabbit mAb
Clone No.JM30-17
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesKPCD1_HUMAN antibody
nPKC D1 antibody
nPKC mu antibody
nPKC-D1 antibody
nPKC-mu antibody
nPKCD1 antibody
nPKCmu antibody
PKC antibody
PKC MU antibody
PKCM antibody
PKCmu antibody
PKD 1 antibody
PKD antibody
PKD1 antibody
PRKCM antibody
PRKD 1 antibody
Prkd1 antibody
Protein kinase C mu antibody
Protein kinase C mu type antibody
Protein kinase D antibody
Protein kinase D1 antibody
Serine/threonine protein kinase D1 antibody
Serine/threonine-protein kinase D1 antibody
Accession NoSwiss-Prot#:Q15139
Uniprot
Q15139
Gene ID
5587;
Calculated MW102 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
Western blot analysis of PKC mu on different cell lysate using anti-PKC mu antibody at 1/1,000 dilution. Positive control��
Lane1: Hela
Lane2: Mouse kidney
Lane3: PC12
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.
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