Product Detail
Product Namealpha 1 Antichymotrypsin Rabbit mAb
Clone No.JM83-29
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, IP
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesSERPINA3 antibody
AACT antibody
AACT_HUMAN antibody
ACT antibody
Alpha-1-antichymotrypsin His-Pro-less antibody
Antichymotrypsin antibody
Cell growth inhibiting gene 24/25 protein antibody
Cell growth-inhibiting gene 24/25 protein antibody
GIG24 antibody
GIG25 antibody
Growth inhibiting protein 24 antibody
Growth inhibiting protein 25 antibody
MGC88254 antibody
Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3 antibody
Serine (or cysteine) proteinase inhibitor clade A member 3 antibody
Serine proteinase inhibitor clade A member 3 antibody
Serpin A3 antibody
Serpin family A member 3 antibody
Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 antibody
SERPINA3 antibody
Accession NoSwiss-Prot#:P01011
Uniprot
P01011
Gene ID
12;
Calculated MW60 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
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