Product Detail
Product NameGABARAP Rabbit mAb
Clone No.JM30-30
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, FC
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesATG8A antibody
FLC 3B antibody
FLC3B antibody
FLJ25768 antibody
GABA type A receptor associated protein antibody
GABA(A) receptor associated protein antibody
GABA(A) receptor-associated protein antibody
GABARAP a antibody
GABARAP antibody
Gamma aminobutyric acid receptor associated protein antibody
Gamma-aminobutyric acid receptor-associated protein antibody
GBRAP_HUMAN antibody
MGC120154 antibody
MGC120155 antibody
MM 46 antibody
MM46 antibody
Accession NoSwiss-Prot#:O95166
Uniprot
O95166
Gene ID
11337;
Calculated MW14 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100
Western blot analysis of GABARAP on mouse kidney (1) and rat liver (2) tissue lysate using anti-GABARAP antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-GABARAP antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GABARAP antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GABARAP antibody. Counter stained with hematoxylin.
Flow cytometric analysis of Hela cells with GABARAP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.
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