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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Angiopoietin 2 Rabbit mAb

Angiopoietin 2 Rabbit mAb#49649

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Product Detail

Product NameAngiopoietin 2 Rabbit mAb

Clone No.JM71-34

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAGPT 2 antibody
Agpt2 antibody
ANG 2 antibody
ANG-2 antibody
ANG2 antibody
Angiopoietin 2a antibody
Angiopoietin 2B antibody
Angiopoietin-2 antibody
Angiopoietin2 antibody
ANGP2_HUMAN antibody
ANGPT 2 antibody
Angpt2 antibody
Tie2 ligand antibody

Accession NoSwiss-Prot#:O15123

Uniprot O15123

Gene ID 285;

Calculated MW50 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200


Western blot analysis of Angiopoietin 2 on different cell lysate using anti-Angiopoietin 2 antibody at 1/1,000 dilution. Positive control��
Lane1: TF-1
Lane2: Human liver tissue
Lane3: Human placenta tissue
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Angiopoietin 2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-Angiopoietin 2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Angiopoietin 2 antibody. Counter stained with hematoxylin.
Tie-1 and Tie-2 (also designated Tek) are novel cell surface receptor tyrosine kinases. The extracellular domain of Tie-1 has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three fibronectin type III repeats next to the transmembrane region. Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2. Preliminary biochemical analyses of Ang-1 reveal a potential fibrinogen-like domain at the carboxy terminus and coiled-coil regions in the amino terminus. Ang-1 is an angiogenic factor that is thought to be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), has been identified as a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression seems to be restricted to sites of vascular remodeling.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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