Product Detail
Product NameWDR5 Rabbit mAb
Clone No.JM73-53
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, FC
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Names2410008O07Rik antibody
AA408785 antibody
AA960360 antibody
BIG 3 antibody
Big antibody
BIG3 antibody
BMP2 induced 3 kb gene protein antibody
BMP2 induced gene, 3-KB antibody
BMP2-induced 3-kb gene protein antibody
MGC114572 antibody
OTTHUMP00000162494 antibody
SWD 3 antibody
SWD3 antibody
SWD3 Set1c WD40 repeat protein homolog antibody
WD repeat containing protein 5 antibody
WD repeat domain 5 antibody
WD repeat protein 5 antibody
WD repeat-containing protein 5 antibody
WD repeat-containing protein BIG-3 antibody
WDR 5 antibody
Wdr5 antibody
WDR5_HUMAN antibody
Accession NoSwiss-Prot#:P61964
Uniprot
P61964
Gene ID
11091;
Calculated MW36 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1000
IHC: 1:50-1:200
FC: 1:50-1:100
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
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Yes
