Product Detail
Product NameRRM2 Rabbit mAb
Clone No.JM93-43
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IP, ICC/IF
Species ReactivityHu
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other Namescb111 antibody
chunp6884 antibody
etID309896.20 antibody
R2 antibody
reductase M2 polypeptide variant 1 antibody
reductase M2 polypeptide variant 2 antibody
reductase M2 polypeptide variant 3a antibody
reductase M2 polypeptide variant 3b antibody
reductase M2 polypeptide variant 3c antibody
reductase M2 polypeptide variant 3d antibody
Ribonucleoside-diphosphate reductase subunit M2 antibody
Ribonucleotide reductase M2 antibody
Ribonucleotide reductase M2 polypeptide antibody
Ribonucleotide reductase M2 subunit antibody
ribonucleotide reductase protein r2 class I antibody
Ribonucleotide reductase regulatory subunit M2 antibody
Ribonucleotide reductase small chain antibody
Ribonucleotide reductase small subunit antibody
Ribonucleotide reductase, R2 subunit antibody
RIR2_HUMAN antibody
RR2 antibody
RR2M antibody
RRM2 antibody
Accession NoSwiss-Prot#:P31350
Uniprot
P31350
Gene ID
6241;
Calculated MW45 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
ICC: 1:20-1:50
IP: 1:10-1:50
Belongs to the ribonucleoside diphosphate reductase small chain family. Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.it have two regulatory sites: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.
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