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mtTFA Rabbit mAb#49654

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Product Detail

Product NamemtTFA Rabbit mAb

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP

Species ReactivityHu

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other Namesanscription factor 6-like 1 antibody
Mitochondrial transcription factor 1 antibody
mitochondrial transcription factor A antibody
MtTF1 antibody
mtTFA antibody
TCF 6 antibody
TCF-6 antibody
TCF6 antibody
TCF6L1 antibody
TCF6L2 antibody
TCF6L3 antibody
TFAM antibody
TFAM_HUMAN antibody
Transcription factor 6 antibody
Transcription factor 6 like 2 (mitochondrial transcription factor) antibody
Transcription factor 6 like 2 antibody
Transcription factor 6-like 2 antibody
transcription factor 6-like 3 antibody
Transcription factor A, mitochondrial antibody
Transcription factor A, mitochondrial antibody
Transcription factor A, mitochondrial precursor antibody

Accession NoSwiss-Prot#:Q00059

Uniprot Q00059

Gene ID 7019;

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:200-1:500
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IP: 1:10-1:50
Western blot analysis of mtTFA on Hela cell using anti-mtTFA antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-mtTFA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-mtTFA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-mtTFA antibody. Counter stained with hematoxylin.
ICC staining mtTFA in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining mtTFA in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining mtTFA in SK-Br-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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