Product Detail
Product NamePGC1 beta Rabbit mAb
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IP, FC
Species ReactivityHu, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesPERC antibody
peroxisome proliferative activated receptor, gamma, coactivator 1, antibody
peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody
Peroxisome proliferator-activated receptor gamma coactivator 1-beta antibody
peroxisome proliferator-activated receptor gamma, coactivator 1 beta antibody
PGC-1(beta) antibody
PGC-1-beta antibody
PGC-1-related estrogen receptor alpha coactivator antibody
PGC1 antibody
PPAR gamma coactivator-1beta antibody
PPAR-gamma coactivator 1-beta antibody
PPARGC-1-beta antibody
PPARGC1 antibody
Ppargc1b antibody
PRGC2_HUMAN antibody
Accession NoSwiss-Prot#:Q86YN6
Uniprot
Q86YN6
Gene ID
133522;
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IP: 1:10-1:50
FC: 1:50-1:200
Western blot analysis of PGC1 beta on rat spleen tissue lysate using anti-PGC1 beta antibody at 1/1,000 dilution.
Flow cytometric analysis of HL-60 cells with PGC1 beta antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
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