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Location： Home > Recombinant Rabbit Monoclonal Antibodies > RANTES Rabbit mAb

RANTES Rabbit mAb#49661

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Product Detail

Product NameRANTES Rabbit mAb

Clone No.JM03-45

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB,ICC,IF,IHC

Species ReactivityHu, Ms

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesBeta chemokine RANTES antibody
Beta chemokine RANTES precursor antibody
C C motif chemokine 5 antibody
CCL 5 antibody
CCL5 antibody
CCL5_HUMAN antibody
Chemokine (C C motif) ligand 5 antibody
Chemokine CC Motif Ligand 5 antibody
D17S136E antibody
EoCP antibody
Eosinophil chemotactic cytokine antibody
MGC17164 antibody
RANTES(4-68) antibody
Regulated upon activation normally T expressed and presumably secreted antibody
SCYA 5 antibody
SCYA5 antibody
SIS delta antibody
SIS-delta antibody
SISd antibody
Small inducible cytokine A5 (RANTES) antibody
Small inducible cytokine A5 antibody
Small inducible cytokine subfamily A (Cys Cys) member 5 antibody
Small-inducible cytokine A5 antibody
T cell specific protein p288 antibody
T cell specific RANTES protein antibody
T cell-specific protein P228 antibody
T-cell-specific protein RANTES antibody
TCP 228 antibody
TCP228 antibody

Accession NoSwiss-Prot#:P13501

Uniprot P13501

Gene ID 6352;

Calculated MW10 kDa

Concentration1 mg/ml

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Western blot analysis of RANTES on mouse thymus tissue lysate using anti-RANTES antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-RANTES antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-RANTES antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human lung caner tissue using anti-RANTES antibody. Counter stained with hematoxylin.
ICC staining RANTES in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining RANTES in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

If you have published an article using product 49661, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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