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Location： Home > Recombinant Rabbit Monoclonal Antibodies > TXNIP Rabbit mAb

TXNIP Rabbit mAb#49663

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Product Detail

Product NameTXNIP Rabbit mAb

Clone No.JM60-35

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, FC

Species ReactivityHu, Ms, Rt

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesEST01027 antibody
HHCPA78 antibody
THIF antibody
Thioredoxin binding protein 2 antibody
Thioredoxin interacting protein antibody
Thioredoxin-binding protein 2 antibody
Thioredoxin-interacting protein antibody
TXNIP antibody
TXNIP_HUMAN antibody
Upregulated by 1,25 dihydroxyvitamin D 3 antibody
VDUP1 antibody
Vitamin D3 up-regulated protein 1 antibody

Accession NoSwiss-Prot#:Q9H3M7

Uniprot Q9H3M7

Gene ID 10628;

Calculated MW44 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

FC: 1:50-1:100
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

If you have published an article using product 49663, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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