Product Detail
Product NameDynein intermediate chain 1 Rabbit mAb
Clone No.JM11-38
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesAxonemal dynein intermediate chain 1 antibody
Axonemal dynein intermediate chain 2 antibody
CILD 1 antibody
CILD1 antibody
Cytoplasmic dynein 1 intermediate chain 1 antibody
Cytoplasmic dynein 1 intermediate chain 2 antibody
Cytoplasmic dynein intermediate chain 1 antibody
Cytoplasmic dynein intermediate chain 2 antibody
DH IC 1 antibody
DH IC 2 antibody
DIC1 antibody
DNAI 1 antibody
DNAI 2 antibody
DNAI1 antibody
DNAI1_HUMAN antibody
DNAI2 antibody
DNCI 2 antibody
DNCI1 antibody
DNCI2 antibody
DNCIC 1 antibody
DNCIC 2 antibody
DNCIC1 antibody
DNCIC2 antibody
DYNC1I1 antibody
DYNC1I2 antibody
Dynein axonemal intermediate chain 1 antibody
Dynein axonemal intermediate polypeptide 1 antibody
Dynein axonemal intermediate polypeptide 2 antibody
Dynein cytoplasmic intermediate polypeptide 1 antibody
Dynein cytoplasmic intermediate polypeptide 2 antibody
Dynein intermediate chain 1 axonemal antibody
Dynein intermediate chain 1 cytosolic antibody
Dynein intermediate chain 1, axonemal antibody
Dynein intermediate chain 2 axonemal antibody
Dynein intermediate chain 2 cytosolic antibody
Dynein intermediate chain DNAI1 antibody
IC74 antibody
ICS antibody
ICS1 antibody
Immotile cilia syndrome 1 antibody
MGC26204 antibody
PCD antibody
Accession NoSwiss-Prot#:Q9UI46
Uniprot
Q9UI46
Gene ID
27019;
Calculated MW79 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1000
IHC: 1:50-1:200
Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dyneins, such as Dynein IC1, cytosolic and Dynein IC2, cytosolic, comprise an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. This complex performs functions necessary for cell survival, such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).
If you have published an article using product 49670, please notify us so that we can cite your literature.
Yes
