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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Estrogen Inducible Protein pS2 Rabbit mAb

Estrogen Inducible Protein pS2 Rabbit mAb#49675

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Product Detail

Product NameEstrogen Inducible Protein pS2 Rabbit mAb

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP, FC

Species ReactivityHu

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesBCEI antibody
Breast cancer estrogen inducible protein antibody
Breast cancer estrogen inducible sequence antibody
Breast cancer estrogen-inducible protein antibody
D21S21 antibody
Gastrointestinal trefoil protein antibody
Gastrointestinal trefoil protein pS2 antibody
hP1.A antibody
HP1A antibody
HPS 2 antibody
HPS2 antibody
pNR 2 antibody
PNR-2 antibody
pNR2 antibody
Polypeptide P1.A antibody
Protein pS2 antibody
PS 2 antibody
pS2 antibody
pS2 protein antibody
TFF 1 antibody
TFF1 antibody
TFF1_HUMAN antibody
Trefoil factor 1 antibody

Accession NoSwiss-Prot#:P04155

Uniprot P04155

Gene ID 7031;

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IP: 1:10-1:50
FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Estrogen Inducible Protein pS2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Estrogen Inducible Protein pS2 antibody. Counter stained with hematoxylin.
ICC staining Estrogen Inducible Protein pS2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Estrogen Inducible Protein pS2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Estrogen Inducible Protein pS2 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of MCF-7 cells with Estrogen Inducible Protein pS2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

If you have published an article using product 49675, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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