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Location： Home > Recombinant Rabbit Monoclonal Antibodies > MMP3 Rabbit mAb

MMP3 Rabbit mAb#49688

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Product Detail

Product NameMMP3 Rabbit mAb

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms, Rt

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesCHDS6 antibody
Matrix metalloproteinase 3 antibody
Matrix metalloproteinase-3 antibody
MGC126102 antibody
MGC126103 antibody
MGC126104 antibody
MMP 3 antibody
MMP-3 antibody
MMP3 antibody
MMP3_HUMAN antibody
Proteoglycanase antibody
SL-1 antibody
SL1 antibody
STMY antibody
STMY1 antibody
STR1 antibody
Stromelysin 1 antibody
Stromelysin-1 antibody
Transin 1 antibody
Transin-1 antibody

Accession NoSwiss-Prot#:P08254

Uniprot P08254

Gene ID 4314;

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200


Western blot analysis of MMP3 on different lysates using anti-MMP3 antibody at 1/1,000 dilution. Positive control: Lane 1: Human liver
Lane 2: Mouse lung
Lane 3: Rat liver
Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP3 antibody. Counter stained with hematoxylin.
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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