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Location： Home > Recombinant Rabbit Monoclonal Antibodies > CD11b Rabbit mAb

CD11b Rabbit mAb#49692

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Product Detail

Product NameCD11b Rabbit mAb

Clone No.SR4545

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB,ICC,IF,IP,IHC,FC

Species ReactivityHu

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other Namesantigen CD11b (p170) antibody
Antigen CD11b p170 antibody
CD11 antigen like family member B antibody
CD11 antigen-like family member B antibody
CD11b antibody
CD11b/CD18 antibody
CD49d antibody
Cell surface glycoprotein MAC-1 subunit alpha antibody
Complement component 3 receptor 3 subunit antibody
Complement Component Receptor 3 Alpha antibody
Complement receptor type 3, alpha subunit antibody
CR 3 alpha chain (CR3A) antibody
CR 3 alpha chain antibody
CR-3 alpha chain antibody
CR3 antibody
CR3A antibody
F730045J24Rik antibody
Integrin Alpha M antibody
Integrin alpha M chain antibody
Integrin alpha-M antibody
Integrin beta 2 alpha subunit antibody
Integrin subunit alpha M antibody
integrin, alpha M (complement component 3 receptor 3 subunit) antibody
ITAM_HUMAN antibody
ITGAM antibody
Leukocyte adhesion receptor MO1 antibody
Ly-40 antibody
MAC 1 antibody
Mac-1a antibody
MAC1 antibody
Mac1, alpha subunit antibody
MAC1A antibody
Macrophage antigen alpha polypeptide antibody
MGC117044 antibody
Mo1, alpha subunit antibody
MO1A antibody
Neutrophil adherence receptor alpha M subunit antibody
Neutrophil adherence receptor antibody
SLEB6 antibody

Accession NoSwiss-Prot#:P11215

Uniprot P11215

Gene ID 3684;

Calculated MW170 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11b antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11b antibody. Counter stained with hematoxylin.
ICC staining CD11b in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of THP-1 cells with CD11b antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

If you have published an article using product 49692, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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