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GluR2 Rabbit mAb#49694

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Product Detail

Product NameGluR2 Rabbit mAb

Clone No.JU20-43

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB,ICC,IF,IHC,IP

Species ReactivityHu, Ms, Rt

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesAMPA 2 antibody
AMPA selective glutamate receptor 2 antibody
AMPA-selective glutamate receptor 2 antibody
AMPA2 antibody
GluA2 antibody
GLUR 2 antibody
GLUR B antibody
GluR K2 antibody
GluR-2 antibody
GluR-B antibody
GluR-K2 antibody
GLUR2 antibody
GLURB antibody
Glutamate receptor 2 antibody
Glutamate receptor ionotropic AMPA 2 antibody
Glutamate receptor ionotropic antibody
Gria2 antibody
GRIA2_HUMAN antibody
HBGR2 antibody

Accession NoSwiss-Prot#:P42262

Uniprot P42262

Gene ID 2891;

Calculated MW110 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:50-1:200
ICC: 1:50-1:200

Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GluR2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-GluR2 antibody. Counter stained with hematoxylin.
ICC staining GluR2 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining GluR2 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Lonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

If you have published an article using product 49694, please notify us so that we can cite your literature.

et al,Butyric acid precursor tributyrin modulates hippocampal synaptic plasticity and prevents spatial memory deficits: role of PPARγ and AMPK. In Int J Neuropsychopharmacol on 2022 Jun 21 by Ana Belén Sanz-Martos, Jesús Fernández-Felipe, et al..PMID:35152284 , (2022),
PMID: 35152284

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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