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Location： Home > Phospho Antibodies > ERK1/2 (Phospho-Thr202/Thr185) Rabbit mAb

ERK1/2 (Phospho-Thr202/Thr185) Rabbit mAb#52094

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Product NameERK1/2 (Phospho-Thr202/Thr185) Rabbit mAb

Clone No.S05-2H9

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity Purified

ApplicationsWB

Species ReactivityHuman,Mouse,Rat

Immunogen DescA synthetic phosphopeptide corresponding to residues surrounding Thr185 of human ERK2

ConjugateUnconjugated

Other NamesERK1 ERT2 ERK-1 PRKM3 P44ERK1

Accession NoSwiss-Prot:P27361 P28482
GeneID:5594

Uniprot P27361 P28482

Gene ID 5594

Calculated MWCalculated MW: 41 kDa; Observed MW: 44,42 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/1000;
Western blot detection of Phospho-p44/42 MAPK (ERK1/2) (Thr202) in C6,CHO-K1 cell lysates using Phospho-p44/42 MAPK (ERK1/2) (Thr202) Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:44,42kDa.
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

If you have published an article using product 52094, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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