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Location： Home > Phospho Antibodies > Glutamate Receptor 1 (Phospho-AMPA Subtype) (Phospho-Ser845) Rabbit mAb

Glutamate Receptor 1 (Phospho-AMPA Subtype) (Phospho-Ser845) Rabbit mAb#52139

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Product NameGlutamate Receptor 1 (Phospho-AMPA Subtype) (Phospho-Ser845) Rabbit mAb

Clone No.S03-7G4

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity Purified

ApplicationsWB

Species ReactivityHuman,Mouse,Rat

Immunogen DescA synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)

ConjugateUnconjugated

Other NamesGLUH1; GLUR1; GLURA; GluA1; HBGR1

Accession NoSwiss-Prot:P42261
GeneID:2890

Uniprot P42261

Gene ID 2890

Calculated MWPredicted band size: 102 kDa

Sdspage MWObserved band size: 102 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1:500-1:2000
All lanes : Glutamate Receptor 1 (Phospho-AMPA Subtype) (Phospho-Ser845) Rabbit mAb at 1/1k dilution
Lane 1 : Mouse Brain lysates
Lane 2 : Rat Brain lysates
Lane 3 : Human brain lysates treated with Lambda Protein Phosphatase for 30min
Lane 4 : Human brain lysates
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution
Predicted band size: 102 kDa
Observed band size: 102 kDa

Exposure time: 9 seconds
Swiss-Prot Acc.P42261.Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

If you have published an article using product 52139, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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