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Phospholipase A2 Activator Protein Rabbit mAb#52504

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Product NamePhospholipase A2 Activator Protein Rabbit mAb

Clone No.S06-1D7

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity Purified

ApplicationsWB

Species ReactivityHuman

Immunogen DescA synthetic peptide of human Anti-Phospholipase A2 activator protein (PLAP)

ConjugateUnconjugated

Other NamesDOA1; PLAP; PLA2P; NDMSBA

Accession NoSwiss-Prot:Q9Y263
GeneID:9373

Uniprot Q9Y263

Gene ID 9373

Calculated MWCalculated MW: 87 kDa; Observed MW: 87 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/1000;
Western blot detection of Phospholipase A2 activator protein (PLAP) in 3T3,Hela cell lysates using Phospholipase A2 activator protein (PLAP) Rabbit mAb(1:1000 diluted).Predicted band size:87kDa.Observed band size:87kDa.
Swiss-Prot Acc.Q9Y263.Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling . May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). Plays a role in cerebellar Purkinje cell development . Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986).

If you have published an article using product 52504, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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