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Phospholipase C gamma 1 Rabbit mAb#52837

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Product Detail

Product NamePhospholipase C gamma 1 Rabbit mAb

Clone No.S01-6B4

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

IsotypeIgG

PurificationAffinity Purified

ApplicationsWB

Species ReactivityHuman,Mouse,Rat

Immunogen DescA synthetic peptide of human Phospholipase C gamma 1/PLC-gamma-1

ConjugateUnconjugated

Other NamesPLC1; NCKAP3; PLC-II; PLC148; PLCgamma1

Accession NoSwiss-Prot:P19174
GeneID:5335

Uniprot P19174

Gene ID 5335

Calculated MWCalculated MW:149 kDa,Observed MW:149 kDa

Concentration0.3 mg/ml

Formulation50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

StorageStore at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

Application Details
WB: 1/2000
Western blot detection of Phospholipase C gamma 1/PLC-gamma-1 in U2OS,C6 using Phospholipase C gamma 1/PLC-gamma-1 Rabbit mAb(1:1000 diluted)
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (PubMed:17229814).

If you have published an article using product 52837, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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