Product Detail
Product NameHistone H2AX Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant protein of human Histone H2AX.
ConjugateUnconjugated
Other NamesH2A.X;H2A/X;H2AX;Histone H2AX;H2AFX;histone H2AX;gamma H2A.X;��H2AX
Accession NoSwiss Prot:P16104
Gene ID:3014
Uniprot
P16104
Gene ID
3014
Calculated MW15kDa
Sdspage MW15kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Histone H2AX antibody.
Immunohistochemistry of paraffin-embedded mouse brain using Histone H2AX antibody.
Immunohistochemistry of paraffin-embedded rat heart using Histone H2AX antibody.
Immunohistochemistry of paraffin-embedded rat brain using Histone H2AX antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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