Product Detail
                                
                                                                        Product NameCD68 Rabbit Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC,IF
                                        Species ReactivityHuman,Mouse,Rat
                                                                                                                         Immunogen DescRecombinant fusion protein of human CD68 (NP_001242.2).     
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesCD68;GP110;LAMP4;SCARD1
                                        Accession NoSwiss Prot:P34810
GeneID:968
                                        Uniprot
                                        P34810
                                        
                                                                                Calculated MW31kDa/34kDa/37kDa
                                        Sdspage MW80-110KDa
                                                                                 FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:2000
IHC	1:50 - 1:200
IF	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded Human oophoroma using CD68  at dilution of 1:100 (40x lens).
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded Mouse spleen using CD68  at dilution of 1:100 (40x lens).
                                 
                                                                
                                    
                                    Western blot analysis of extracts of various cell lines, using CD68 Polyclonal  at 1:1000 dilution.
                                 
                                                                
                                    
                                    Western blot analysis of extracts of Rat thymus, using CD68 Polyclonal  at 1:1000 dilution.
                                 
                                                             
                            
                                This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. 
                            
                            
                                If you have published an article using product 53543, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,Engineering extracellular vesicles derived from endothelial cells sheared by laminar flow for anti-atherosclerotic therapy through reprogramming macrophage.
 ,  (2025),
PMID:
                                    39270628