Product Detail
Product NamePDK4 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human PDK4 (NP_002603.1).
ConjugateUnconjugated
Other NamesPDK4
Accession NoSwiss Prot:Q16654
Gene ID:5166
Uniprot
Q16654
Gene ID
5166
Calculated MW46kDa
Sdspage MW46KDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PDK4 antibody.
Immunohistochemistry of paraffin-embedded rat heart using PDK4 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human placenta using PDK4 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse heart using PDK4 Rabbit pAb.
Immunofluorescence analysis of C6 cells using PDK4 antibody.
Immunofluorescence analysis of L929 cells using PDK4 antibody.
Immunofluorescence analysis of U-2 OS cells using PDK4 antibody.
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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