Product Detail
Product NameTBL1XR1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse
Immunogen DescRecombinant fusion protein of human TBL1XR1 (NP_078941.2).
ConjugateUnconjugated
Other NamesTBL1XR1;C21;DC42;IRA1;MRD41;TBLR1
Accession NoSwiss Prot:Q9BZK7
Gene ID:79718
Uniprot
Q9BZK7
Gene ID
79718
Calculated MW55kDa
Sdspage MW55-70kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TBL1XR1 antibody.
Immunofluorescence analysis of A549 cells using TBL1XR1 antibody.
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
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