Product Detail
Product NameSERPINH1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse
Immunogen DescRecombinant fusion protein of human HSP47/HSP47/SERPINH1 (NP_001226.2).
ConjugateUnconjugated
Other NamesSERPINH1;AsTP3;CBP1;CBP2;HSP47;OI10;PIG14;PPROM;RA-A47;SERPINH2;gp46;serpin H1
Accession NoUniprot:P50454
GeneID:871
Uniprot
P50454
Gene ID
871
Calculated MW46kDa
Sdspage MW46KDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using HSP47/SERPINH1 antibody.
Immunofluorescence analysis of NIH/3T3 cells using HSP47/SERPINH1 Rabbit pAb.
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
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