Product Detail
Product NameIFIH1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human IFIH1 (NP_071451.2).
ConjugateUnconjugated
Other NamesIFIH1;AGS7;Hlcd;IDDM19;MDA-5;MDA5;RLR-2;SGMRT1
Accession NoUniprot:Q9BYX4
GeneID:64135
Uniprot
Q9BYX4
Gene ID
64135
Calculated MW25kDa/116kDa
Sdspage MW140KDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of BxPC-3 cells, using IFIH1 antibody.
Immunohistochemistry of paraffin-embedded human esophageal cancer using IFIH1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human placenta using IFIH1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse spleen using IFIH1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat lung using IFIH1 Rabbit pAb.
Immunofluorescence analysis of THP-1 cells using IFIH1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse lung using IFIH1 Rabbit pAb.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
If you have published an article using product 53689, please notify us so that we can cite your literature.