Product Detail
Product NameSIRT3 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human SIRT3 (NP_036371.1).
ConjugateUnconjugated
Other NamesSIRT3;SIR2L3;sirtuin 3
Accession NoSwiss Prot:Q9NTG7
Gene ID:23410
Uniprot
Q9NTG7
Gene ID
23410
Calculated MW28kDa/43kDa
Sdspage MWRefer to figures
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human colon carcinoma using SIRT3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using SIRT3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat kidney using SIRT3 Rabbit pAb.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
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