Product Detail
Product NameMRPS7 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human MRPS7 (NP_057055.2).
ConjugateUnconjugated
Other NamesMRPS7;MRP-S;MRP-S7;RP-S7;RPMS7;S7mt;bMRP27a
Accession NoSwiss Prot:Q9Y2R9
Gene ID:51081
Uniprot
Q9Y2R9
Gene ID
51081
Calculated MW28kDa
Sdspage MW28kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MRPS7 Rabbit pAb.
Immunofluorescence analysis of C6 cells using MRPS7 antibody.
Immunofluorescence analysis of L929 cells using MRPS7 antibody.
Immunofluorescence analysis of U-2 OS cells using MRPS7 antibody.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
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