Product Detail
Product NameRBFOX3 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityMouse,Rat
Immunogen DescRecombinant fusion protein of human RBFOX3 (NP_001076045.1).
ConjugateUnconjugated
Other NamesFOX-3;FOX3;HRNBP3;NEUN;NeuN;RBFOX3
Accession NoSwiss Prot:A6NFN3
Gene ID:146713
Uniprot
A6NFN3
Gene ID
146713
Calculated MW33kDa/35kDa
Sdspage MWRefer to figures
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
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