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Location： Home > Polyclonal Antibodies > IL1 beta Rabbit Polyclonal Antibody

IL1 beta Rabbit Polyclonal Antibody#54413

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Product Detail

Product NameIL1 beta Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant protein of human IL1 beta.

ConjugateUnconjugated

Other NamesIL-1;IL1-BETA;IL1F2;IL1 beta;IL1B

Accession NoSwiss Prot:P01584
GeneID:3553

Uniprot P01584

Calculated MW30kDa

Sdspage MW37kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cells, using IL1 beta at 1:1000 dilution.
Immunofluorescence analysis of mouse spleen using IL1 beta at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of rat spleen using IL1 beta at dilution of 1:100. Blue: DAPI for nuclear staining.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

If you have published an article using product 54413, please notify us so that we can cite your literature.

et al,p300 upregulates Ikur in atrial cardiomyocytes through activating NLRP3 inflammasome in hypertension. , (2025),
PMID: 39966999

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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