Product Detail
Product NameCAPN7 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human CAPN7 (NP_055111.1).
ConjugateUnconjugated
Other NamesCALPAIN7;PALBH;CAPN7;calpain-7
Accession NoSwiss Prot:Q9Y6W3
Gene ID:23473
Uniprot
Q9Y6W3
Gene ID
23473
Calculated MW92kDa
Sdspage MW93kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of Jurkat cells, using CAPN7 Rabbit pAb.
Immunofluorescence analysis of A431 cells using CAPN7 antibody.
Immunofluorescence analysis of L929 cells using CAPN7 antibody.
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]
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