Product Detail
Product NamePKM2-specific Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant protein of human PKM2-specific.
ConjugateUnconjugated
Other NamesPK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1;
Accession NoSwiss Prot:P14618
Gene ID:5315
Uniprot
P14618
Gene ID
5315
Calculated MW56kDa/57kDa/58kDa
Sdspage MW58kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PKM2-specific antibody.
Immunofluorescence analysis of C6 cells using PKM2-specific Rabbit pAb.
Immunofluorescence analysis of HeLa cells using PKM2-specific Rabbit pAb.
Immunofluorescence analysis of NIH-3T3 cells using PKM2-specific Rabbit pAb.
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
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