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Location： Home > Polyclonal Antibodies > NTRK1/NTRK2/NTRK3 Rabbit Polyclonal Antibody

NTRK1/NTRK2/NTRK3 Rabbit Polyclonal Antibody#54597

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Product Detail

Product NameNTRK1/NTRK2/NTRK3 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant protein of human NTRK1/NTRK2/NTRK3.

ConjugateUnconjugated

Other Names_

Accession NoSwiss Prot:P04629/Q16620/Q16288
Gene ID:4914/4915/4916

Uniprot P04629/Q16620/Q16288

Gene ID 4914/4915/4916

Calculated MW_

Sdspage MW100KDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using NTRK1\NTRK2\NTRK3 antibody.
Immunofluorescence analysis of C6 cells using NTRK1\NTRK2\NTRK3 Rabbit pAb.
Immunofluorescence analysis of NIH-3T3 cells using NTRK1\NTRK2\NTRK3 Rabbit pAb.
Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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