Product Detail
Product NameRHOG Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant protein of human RHOG.
ConjugateUnconjugated
Other NamesARHG;RHOG
Accession NoSwiss Prot:P84095
Gene ID:391
Uniprot
P84095
Gene ID
391
Calculated MW_
Sdspage MWRefer to figures
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human liver cancer using RHOG antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using RHOG antibody.
Immunohistochemistry of paraffin-embedded human appendix using RHOG antibody.
Immunofluorescence analysis of L929 cells using RHOG Rabbit pAb.
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011]
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