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PLP1 Rabbit Polyclonal Antibody#54631

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Product Detail

Product NamePLP1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityMouse,Rat

Immunogen DescRecombinant fusion protein of human PLP1 (NP_955772.1).

ConjugateUnconjugated

Other NamesPLP1;GPM6C;HLD1;MMPL;PLP;PLP/DM20;PMD;SPG2

Accession NoSwiss Prot:P60201
Gene ID:5354

Uniprot P60201

Gene ID 5354

Calculated MW26kDa/30kDa

Sdspage MW20-25kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PLP1 antibody.
Immunohistochemistry of paraffin-embedded rat brain using PLP1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse brain using PLP1 Rabbit pAb.
Immunofluorescence analysis of rat brain using PLP1 Rabbit pAb.
Immunofluorescence analysis of mouse brain using PLP1 Rabbit pAb.
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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