Product Detail
Product NamePLP1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityMouse,Rat
Immunogen DescRecombinant fusion protein of human PLP1 (NP_955772.1).
ConjugateUnconjugated
Other NamesPLP1;GPM6C;HLD1;MMPL;PLP;PLP/DM20;PMD;SPG2
Accession NoSwiss Prot:P60201
Gene ID:5354
Uniprot
P60201
Gene ID
5354
Calculated MW26kDa/30kDa
Sdspage MW20-25kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PLP1 antibody.
Immunohistochemistry of paraffin-embedded rat brain using PLP1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse brain using PLP1 Rabbit pAb.
Immunofluorescence analysis of rat brain using PLP1 Rabbit pAb.
Immunofluorescence analysis of mouse brain using PLP1 Rabbit pAb.
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
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