Product Detail
Product NameRING1A Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant protein of human RING1AA.
ConjugateUnconjugated
Other NamesRNF1; RING1A
Accession NoSwiss Prot:Q06587
Gene ID:6015
Uniprot
Q06587
Gene ID
6015
Calculated MW42kDa
Sdspage MW54KDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using RING1A antibody.
Western blot analysis of extracts of Rat lung, using RING1A antibody.
Immunohistochemistry of paraffin-embedded human brain using RING1A Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse stomach using RING1A Rabbit pAb.
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
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