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Location： Home > Polyclonal Antibodies > IGF2BP3 Rabbit Polyclonal Antibody

IGF2BP3 Rabbit Polyclonal Antibody#54968

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Product Detail

Product NameIGF2BP3 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human IGF2BP3 (NP_006538.2).

ConjugateUnconjugated

Other NamesIGF2BP3;CT98;IMP-3;IMP3;KOC;KOC1;VICKZ3

Accession NoSwiss Prot:O00425
GeneID:10643

Uniprot O00425

Calculated MW21kDa/63kDa

Sdspage MW70kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:20 - 1:50
Western blot analysis of extracts of various cell lines, using IGF2BP3 at 1:1000 dilution.
Immunofluorescence analysis of L929 cells using IGF2BP3 at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat testis using IGF2BP3 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse testis using IGF2BP3 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using IGF2BP3 at dilution of 1:100 (40x lens).
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

If you have published an article using product 54968, please notify us so that we can cite your literature.

et al,Necroptosis-Related Prognostic Model for Pancreatic Carcinoma Reveals Its Invasion and Metastasis Potential through Hybrid EMT and Immune EscapeInBiomedicinesOn2023 Jun 16byHaichuan Liu?1,?Zhenghang Li et al..PMID:?37371833 , (2023),
PMID: 37371833
et al,Depletion of the N6-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4. In Cell Death Dis on 2024 Mar 1 by Limei Deng, Yunbo Di,et al..PMID:38429265 , (2024),
PMID: 38429265

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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