Product Detail
                                
                                                                        Product NameCCL8 Rabbit Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC,IF
                                        Species ReactivityHuman,Mouse
                                                                                                                         Immunogen DescRecombinant fusion protein of human CCL8 (NP_005614.2).     
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesCCL8;HC14;MCP-2;MCP2;SCYA10;SCYA8
                                        Accession NoSwiss Prot:P80075
GeneID:6355
                                        Uniprot
                                        P80075
                                        
                                                                                Calculated MW11kDa
                                                                                                                         FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:2000
IHC	1:50 - 1:100
IF	1:50 - 1:100
                             
                            
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human liver using CCL8  at dilution of 1:100 (40x lens).
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human prostate cancer using CCL8  at dilution of 1:100 (40x lens).
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human stomach using CCL8  at dilution of 1:100 (40x lens).
                                 
                                                             
                            
                                This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. 
                            
                            
                                If you have published an article using product 55062, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice.
 ,  (2025),
PMID:
                                    39774471