Product Detail
Product NameHDAC7 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescA synthetic peptide of human HDAC7 (NP_056216.2).
ConjugateUnconjugated
Other NamesHDAC7;HD7;HD7A;HDAC7A
Accession NoSwiss Prot:Q8WUI4
GeneID:51564
Uniprot
Q8WUI4
Calculated MW46-66kDa/99-108kDa
Sdspage MW120kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using HDAC7 at 1:1000 dilution.
Western blot analysis of extracts of various cell lines, using HDAC7 at 1:1000 dilution.
Immunofluorescence analysis of MCF-7 cells using HDAC7 . Blue: DAPI for nuclear staining.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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