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DFNA5/GSDME Rabbit Polyclonal Antibody#55212

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Product Detail

Product NameDFNA5/GSDME Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human DFNA5/GSDME (NP_004394.1).

ConjugateUnconjugated

Other NamesDFNA5;ICERE-1;GSDME

Accession NoSwiss Prot:O60443
Gene ID:1687

Uniprot O60443

Gene ID 1687

Calculated MW36kDa/54kDa

Sdspage MW55kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using DFNA5\GSDME antibody.
Immunohistochemistry of paraffin-embedded Human pulmonary tuberculosis using DFNA5\GSDME Rabbit pAb.
Immunohistochemistry of paraffin-embedded Human pancreatic panniculitis using DFNA5\GSDME Rabbit pAb.
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

If you have published an article using product 55212, please notify us so that we can cite your literature.

et al,Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis. , (2025),
PMID: 39950759

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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