Product Detail
Product NameASPSCR1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human TUG/ASPSCR1 (NP_076988.1).
ConjugateUnconjugated
Other NamesASPSCR1;ASPCR1;ASPL;ASPS;RCC17;TUG;UBXD9;UBXN9
Accession NoUniprot:Q9BZE9
GeneID:79058
Uniprot
Q9BZE9
Gene ID
79058
Calculated MW37kDa/54kDa/60kDa/69kDa
Sdspage MW80kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of HeLa cells using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of NIH/3T3 cells using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of PC-12 cells using TUG/ASPSCR1 antibody.
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
If you have published an article using product 55230, please notify us so that we can cite your literature.