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ASPSCR1 Rabbit Polyclonal Antibody#55230

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Product Detail

Product NameASPSCR1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human TUG/ASPSCR1 (NP_076988.1).

ConjugateUnconjugated

Other NamesASPSCR1;ASPCR1;ASPL;ASPS;RCC17;TUG;UBXD9;UBXN9

Accession NoUniprot:Q9BZE9
GeneID:79058

Uniprot Q9BZE9

Gene ID 79058

Calculated MW37kDa/54kDa/60kDa/69kDa

Sdspage MW80kDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of HeLa cells using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of NIH/3T3 cells using TUG/ASPSCR1 antibody.
Immunofluorescence analysis of PC-12 cells using TUG/ASPSCR1 antibody.
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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