Product Detail
Product NameKRT16 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human Cytokeratin 16 (KRT16) (NP_005548.2).
ConjugateUnconjugated
Other NamesKRT16;CK16;FNEPPK;K16;K1CP;KRT16A;NEPPK;PC1
Accession NoUniprot:P08779
GeneID:3868
Uniprot
P08779
Gene ID
3868
Calculated MW51kDa
Sdspage MW47kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Cytokeratin 16 (KRT16) antibody.
Immunohistochemistry of paraffin-embedded human esophageal cancer using Cytokeratin 16 (KRT16) Rabbit pAb.
Immunofluorescence analysis of A-549 cells using Cytokeratin 16 (KRT16) Rabbit pAb.
Immunofluorescence analysis of mouse skin using Cytokeratin 16 (KRT16) Rabbit pAb.
Immunohistochemistry of paraffin-embedded human skin using Cytokeratin 16 (KRT16) Rabbit pAb.
Immunofluorescence analysis of rat skin using Cytokeratin 16 (KRT16) Rabbit pAb.
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
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