Product Detail
Product NameDVL2 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human DVL2 (NP_004413.1).
ConjugateUnconjugated
Other NamesDVL2
Accession NoSwiss Prot:O14641
GeneID:1856
Uniprot
O14641
Calculated MW78kDa
Sdspage MW95kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunofluorescence analysis of NIH/3T3 cells using DVL2 at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using DVL2 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat heart using DVL2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using DVL2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using DVL2 at dilution of 1:100 (40x lens).
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
If you have published an article using product 55250, please notify us so that we can cite your literature.