Product Detail
Product NameDesmoplakin Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescA synthetic peptide of human Desmoplakin (NP_004406.2).
ConjugateUnconjugated
Other NamesDCWHKTA;DP;DSP
Accession NoSwiss Prot:P15924
GeneID:1832
Uniprot
P15924
Calculated MW260kDa/278kDa/331kDa
Sdspage MW330kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human liver damage using Desmoplakin at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using Desmoplakin at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded Human tonsil using Desmoplakin at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using Desmoplakin at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast cancer using Desmoplakin at dilution of 1:100 (40x lens).
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
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