Product Detail
Product NameIRF1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescA synthetic peptide of human IRF1
ConjugateUnconjugated
Other NamesIRF1;IRF-1;MAR
Accession NoSwiss Prot:P10914
GeneID:3659
Uniprot
P10914
Calculated MW36kDa
Sdspage MW50KDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Immunofluorescence analysis of U-2 OS cells using IRF1 at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human lung cancer using IRF1 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using IRF1 (40x lens).
Western blot analysis of extracts of Rat lung, using IRF1 Polyclonal at 1:1000 dilution.
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
If you have published an article using product 55286, please notify us so that we can cite your literature.