Product Detail
Product NameUBE2A Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human UBE2A (NP_003327.2).
ConjugateUnconjugated
Other NamesUBE2A;HHR6A;MRXS30;MRXSN;RAD6A;UBC2
Accession NoSwiss Prot:P49459
GeneID:7319
Uniprot
P49459
Calculated MW8kDa/13kDa/17kDa
Sdspage MW14kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using UBE2A at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded mouse stomach using UBE2A (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using UBE2A (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using UBE2A (40x lens).
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
If you have published an article using product 55311, please notify us so that we can cite your literature.