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SOCS1 Rabbit Polyclonal Antibody#55318

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Product Detail

Product NameSOCS1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human SOCS1 (NP_003736.1).

ConjugateUnconjugated

Other NamesSOCS1;CIS1;CISH1;JAB;SOCS-1;SSI-1;SSI1;TIP3;TIP-3

Accession NoUniprot:O15524
GeneID:8651

Uniprot O15524

Gene ID 8651

Calculated MW23kDa

Sdspage MW23KDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using SOCS1 antibody.
Immunofluorescence analysis of PC-12 cells using SOCS1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse spleen using SOCS1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat brain using SOCS1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat spleen using SOCS1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human colon carcinoma using SOCS1 Rabbit pAb.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

If you have published an article using product 55318, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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