Product Detail
Product NameGABARAPL2 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human GABARAPL2 (NP_009216.1).
ConjugateUnconjugated
Other NamesGABARAPL2;ATG8;ATG8C;GATE-16;GATE16;GEF-2;GEF2
Accession NoUniprot:P60520
GeneID:11345
Uniprot
P60520
Gene ID
11345
Calculated MW13kDa
Sdspage MW14kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of mouse brain, using GABARAPL2 antibody.
Immunohistochemistry of paraffin-embedded mouse heart using GABARAPL2 antibody.
Immunohistochemistry of paraffin-embedded rat brain using GABARAPL2 antibody.
Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
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