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Location： Home > Polyclonal Antibodies > CHRFAM7A Rabbit Polyclonal Antibody

CHRFAM7A Rabbit Polyclonal Antibody#55344

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Product Detail

Product NameCHRFAM7A Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human CHRFAM7A (NP_647536.1).

ConjugateUnconjugated

Other NamesCHRFAM7A;CHRNA7;CHRNA7-DR1;D-10

Accession NoSwiss Prot:Q494W8
GeneID:89832

Uniprot Q494W8

Calculated MW46kDa

Sdspage MW46kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using CHRFAM7A at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat brain using CHRFAM7A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using CHRFAM7A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using CHRFAM7A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using CHRFAM7A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using CHRFAM7A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse stomach using CHRFAM7A at dilution of 1:100 (40x lens).
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

If you have published an article using product 55344, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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