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Location： Home > Polyclonal Antibodies > PCSK9 Rabbit Polyclonal Antibody

PCSK9 Rabbit Polyclonal Antibody#55348

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Product Detail

Product NamePCSK9 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescA synthetic peptide of human Proprotein Convertase 9(PCSK9) (NP_777596.2).

ConjugateUnconjugated

Other NamesPCSK9;FH3;HCHOLA3;LDLCQ1;NARC-1;NARC1;PC9

Accession NoUniprot:Q8NBP7
GeneID:255738

Uniprot Q8NBP7

Gene ID 255738

Calculated MW20kDa/74kDa

Sdspage MW80KDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Proprotein Convertase 9(PCSK9) antibody.
Immunofluorescence analysis of PC-12 cells using Proprotein Convertase 9(PCSK9) Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using Proprotein Convertase 9(PCSK9) Rabbit pAb.
Immunofluorescence analysis of U2OS cells using Proprotein Convertase 9(PCSK9) Rabbit pAb.
Immunofluorescence analysis of HepG2 cells using Proprotein Convertase 9(PCSK9) Rabbit pAb.
Western blot analysis of extracts of Mouse liver, using Proprotein Convertase 9(PCSK9) antibody.
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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